ethisterone मीनिंग इन हिंदी

उदाहरण वाक्य

1. Closely related analogues of ethisterone include vinyltestosterone, allyltestosterone, methyltestosterone, ethyltestosterone, and propyltestosterone.
2. Vinyltestosterone has been described as a weak AAS, though stronger than its 17?-ethynylated analogue ethisterone.
3. Due to its androgenic activity, ethisterone has been associated with the masculinization of female fetuses in women who have taken it during pregnancy.
4. However, in spite of its improved potency over ethisterone, it is a weak progestogen relative to most other progestins, in fact one of the weakest known.
5. The improved potency of dimethisterone due to 6?-methylation reportedly served as the basis for the synthesis of medroxyprogesterone acetate . medroxyprogesterone acetate shows 10 to 25 times the potency of ethisterone.
6. It was developed in the 1950s and, along with the testosterone derivatives ethisterone, norethisterone, normethandrone, and norethandrolone and the progesterone derivative hydroxyprogesterone acetate, was one of the first orally active progestogens to be developed.
7. Dimethisterone was derived from modification of ethisterone via introduction of methyl groups at the C6? and C21 positions . is a pure progestogen with no androgenic ( or estrogenic ) activity in animals even at very high doses ( although some weak antimineralocorticoid activity was observed at high doses in animals ).
8. Among the testosterone derivatives, and in no particular order, levonorgestrel, norgestrel, norgestrienone, ethisterone, gestrinone, danazol, normethandrone, and norvinisterone have the greatest androgenic activity, while norethisterone and its prodrugs ( norethisterone acetate, norethisterone enanthate, lynestrenol, etynodiol diacetate, and quingestanol acetate ) have moderate activity.
9. It was reasoned that since ethisterone ( 17?-ethinyltestosterone ) is orally active, and since 19-norprogesterone is a very potent progestin parenterally, that 17?-ethynyl-19-nortestosterone ( known now as norethisterone or norethindrone ) might be a potent, orally active progestin, and indeed, this was found to be the case.