allosteric site उदाहरण वाक्य

उदाहरण वाक्य

1. Ketamine appears to inhibit the NMDAR by binding both in the open channel and at an allosteric site.
2. Allosteric sites allow effectors to bind to the protein, often resulting in a conformational change involving protein dynamics.
3. It also binds to the allosteric site of the serotonin transporter, similarly, but less potently than escitalopram.
4. Ganaxolone binds to allosteric sites of the GABA A receptor to modulate and open the hyperpolarization of the neuron.
5. In addition to their high substrates such as cocaine and indatraline have lower affinity for these allosteric sites as well.
6. The allosteric site of AMP binding on muscle isoforms of glycogen phosphorylase are close to the subunit interface just like Ser14.
7. They appear to exert their reuptake inhibition by binding to vaguely characterized allosteric sites on each of the respective monoamine transporters.
8. Allosteric sites are pockets on the enzyme, distinct from the active site, that bind to molecules in the cellular environment.
9. Allosteric activators such as PEP bind to the same allosteric site and facilitate the formation of the T state, thereby inhibiting enzyme activity.
10. For example, when 2, 3-BPG binds to an allosteric site on hemoglobin, the affinity for oxygen of all subunits decreases.