quinolinic acid उदाहरण वाक्य
उदाहरण वाक्य
- Quinolinic acid is a downstream product of the kynurenine pathway, which metabolizes the amino acid tryptophan.
- Quinolinic acid has a potent neurotoxic effect.
- COX-2 inhibitors, such as licofelone have also demonstrated protective properties against the neurotoxic effects of quinolinic acid.
- The quinolinic acid produced in microglia is then released and stimulates NMDA receptors resulting in excitatory neurotoxiticity.
- Neurological changes produced by quinolinic acid injections include altered levels of glutamate, GABA, and other amino acids.
- Norharmane suppresses the production of quinolinic acid, 3-hydroxykynurenine and nitric oxide synthase, thereby acting as a neuroprotectant.
- Quinolinic acid is a byproduct of the kynurenine pathway, which is responsible for catabolism of tryptophan in mammals.
- Levels of quinolinic acid in the CSF of AIDS-dementia can be up to twenty times higher than normal.
- This action is in opposition to the agonist quinolinic acid, another kynurenine, noted for its potential as a neurotoxin.
- Lesions in the pallidum can suppress effects of quinolinic acid in monkeys injected with quinolinic acid into their striatum.