theca cell उदाहरण वाक्य
उदाहरण वाक्य
- Theca cells are located in the ovarian follicles and become luteinized when the ovarian follicle breaks and a new corpus luteum is formed.
- It has a critical role in granulosa cell and theca cell growth, as well as in differentiation and maturation of the oocyte.
- In human embryogenesis, the theca cells form a corpus luteum after a Graafian follicle has expelled its secondary oocyte arrested in second meiosis.
- It is highly expressed in the oocyte and has a pivotal influence on the surrounding somatic cells, particularly granulosa, cumulus and theca cells.
- Theca cells are a group of endocrine cells in the ovary made up of connective tissue surrounding the follicle that has many diverse functions during folliculogenesis.
- The genetic component appears to be inherited in an autosomal dominant fashion with high genetic penetrance but variable ovarian follicle theca cells from women with the allele.
- Hyperthecosis occurs when the cells of the ovarian stroma transition from interstitial cells, which are cells located in between other cells, into luteinized theca cells.
- LH induces the production of androgens by the theca cells, most notably androstendione, which are aromatized by granulosa cells to produce estrogens, primarily estradiol.
- When theca cells form in the tertiary follicle the amount of estrogen increases sharply ( theca-derived androgen is aromatized into estrogen by the granulosa cells ).
- In contrast, granulosa cells lack 17?-hydroxylase and 17, 20-lyase, whereas theca cells express these enzymes and 17?-HSD but lack aromatase.