topoisomerase उदाहरण वाक्य

उदाहरण वाक्य

1. The introduction of DSBs in DNA often employs the topoisomerase-like protein SPO11.
2. It is believed that eukaryotic cells do not contain DNA gyrase or topoisomerase IV.
3. However, when Topoisomerase IV alone was inhibited, decatenation was almost completely blocked.
4. Cadmium has been shown to be carcinogenic due to interactions with DNA topoisomerase II?.
5. It works by blocking the topoisomerase enzyme that is essential for cancer cells to proliferate.
6. Gyrase ( a form of topoisomerase ) relaxes and undoes the supercoiling caused by helicase.
7. Topoisomerase 1 inhibition is synthetically lethal with deficiency of expression of certain DNA repair genes.
8. In cancers, the topoisomerase II-alpha is highly expressed in highly proliferating cells.
9. Both gyrase and topoisomerase IV CTDs bend DNA, but only gyrase introduces negative supercoils.
10. It also shows an antileishmanial activity in animal models being an inhibitor of topoisomerase I.