cyclophilin उदाहरण वाक्य

उदाहरण वाक्य

1. Proteins that contain structural " cis "-prolines in the native state include ribonuclease A, ribonuclease T1, beta lactamase, cyclophilin, and some interleukins.
2. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin.
3. The PPIase family is further divided into three structurally distinct subfamilies : cyclophilin ( CyP ), FK506-binding protein ( FKBP ), and parvulin ( Pvn ).
4. The resulting ciclosporin / cyclophilin complex inhibits the phosphatase activity of calcineurin which in turn is required for the activation of transcription factors that up regulate the expression of inflammatory cytokines.
5. The most commonly used normalizing genes are those that code for the following molecules : tubulin, glyceraldehyde-3-phosphate dehydrogenase, albumin, cyclophilin, and ribosomal RNAs.
6. For these drugs in particular, known immunophilins such as cyclophilin catalyze the " cis-trans " isomerization of peptide bonds, particularly X-Pro peptide bonds.
7. As a cyclophilin, PPIB binds the immunosuppressive drug CsA to form a CsA-cyclophilin complex, which then targets calcineurin to inhibit the signaling pathway for T-cell activation.
8. As a cyclophilin, PPIB binds the immunosuppressive drug CsA to form a CsA-cyclophilin complex, which then targets calcineurin to inhibit the signaling pathway for T-cell activation.
9. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium.
10. As a cyclophilin, PPIF binds the immunosuppressive drug CsA to form a CsA-cyclophilin complex, which then targets calcineurin to inhibit the signaling pathway for T-cell activation.