erythroblast उदाहरण वाक्य
उदाहरण वाक्य
- During this process ICAM-4 binds to VLA-4, an erythroblast binding site, on adjacent erythroblasts and to ?v integrins on macrophages to help stabilise the erythroblastic islands.
- The mRNA from human erythroblasts is ~ 1.4 kilobases long and the transcription start site in erythroid cells has been mapped to 1050 base pairs 5'of the start codon.
- Critical functions in the developing red blood cell ( erythroblast ) include the establishment of the erythroid cytoskeleton, enzymes that mediate heme biosynthesis, and polypeptide chains that constitute the hemoglobin tetramer.
- Subsequent differentiation stages ( proerythroblast to orthochromatic erythroblast ) involve a decrease in cell size and eventual expulsion of the nucleus, and are likely dependent upon EpoR signaling only for their survival.
- These results suggest that Fli-1 overexpression in erythroblasts alters their responsiveness to Epo and triggers abnormal proliferation by switching the signaling event ( s ) associated with terminal differentiation to proliferation.
- "' Sideroblasts "'( "-blast " ) are atypical, abnormal nucleated erythroblasts ( precursors to mature red blood cells ) with granules of iron accumulated in the mitochondria surrounding the nucleus.
- Mice that over expression of NR2F6 in their bone marrow cells have a block at the pro-erythroblast stage of blood cell development both in the bone marrow and in the spleen of animals that have excessive expression of NR2F6.
- At the IBPC, he studied the structure of giant RNA of the messenger type in cells differentiation ( avian erythroblasts ) and formulated the hypothesis of the existence of pre-messengers pre-mRNA by analogy to pre-rRNA.
- In this form of AML, levels of erythroblasts can reach up to 94.8 % of all nucleated cells in the bone marrow, and the immature forms of the erythroblasts, the proerythroblasts and basophilic erythroblasts, are more commonly found.
- In this form of AML, levels of erythroblasts can reach up to 94.8 % of all nucleated cells in the bone marrow, and the immature forms of the erythroblasts, the proerythroblasts and basophilic erythroblasts, are more commonly found.