gyrase उदाहरण वाक्य

उदाहरण वाक्य

1. Fourth-generation fluoroquinolones act at DNA gyrase and topoisomerase IV . This dual action slows development of resistance.
2. In addition, DNA gyrase is needed to relieve the topological stress created by the action of DnaB helicase.
3. Nalidixic acid and related antibiotics inhibit a subunit of DNA gyrase and topoisomerase IV and induce formation of cleavage complexes.
4. Consequently, a different site of MurI, distant from its active site, is involved in interacting with gyrase.
5. The unique ability of gyrase to introduce negative supercoils into DNA is what allows bacterial DNA to have free negative supercoils.
6. DNA gyrase has two subunits, which in turn have two subunits each, i . e . 2A and 2B subunits.
7. While topoisomerase IV does relax positive supercoils like DNA gyrase, it does not introduce further negative supercoiling like the latter enzyme.
8. For gyrase, the structure has a substantial hole in the middle, which is presumed to accommodate the T-segment.
9. This was shown by the inclusion of the racemase substrate L-glutamate in an assay with the separated gyrase inhibition site.
10. Dosages 12 20 mg / kg orally administered for five to ten days . The antibiotic works by inhibiting the enzyme DNA gyrase.