hemolysin उदाहरण वाक्य
उदाहरण वाक्य
- Uropathogenic " E . coli " use P fimbriae ( pyelonephritis-associated alpha-and beta-hemolysins, which cause lysis of urinary tract cells.
- But the fact that hemolysins ( produced by pathogenic microorganisms during infections ) are combined with other virulence factors may threaten a human's life to a greater extent.
- The diarrhetic syndromes observed in patients are thought to stem from the three toxins : hemolysin BL ( Hbl ), nonhemolytic enterotoxin ( Nhe ) and cytotoxin K ( CytK ).
- Many hemolysins are pore-forming toxins ( PFT ), which are able to cause the lysis of erythrocytes, leukocytes, and platelets by producing pores on the cytoplasmic membrane.
- The heptamer of ?-hemolysin from " Staphylococcus aureus " has a mushroom-like shape and measures up to 100 ?in diameter and 100 ?in height.
- Early industrial research into this method was based on a technique called'Exonuclease sequencing', where the readout of electrical signals occurring at nucleotides passing by alpha-hemolysin pores covalently bound with cyclodextrin.
- In this case, it has been proven that alpha-hemolysin takes part in inducing necrotic pulmonary injury by the use of the NLRP3 inflammasome, which is responsible for inflammatory processes and of pyroptosis.
- Premature activation of leukocytes and inhibition of phagocytosis and chemotaxis by alpha-hemolysin, if they occur " in vivo ", would greatly enhance the survival of an E . coli attack.
- Another interesting point is that pretreatment of leukocytes with doses of alpha-hemolysin at which nearly 80 % of the cells survived decreased the ability of the cells to phagocytize bacteria and particles and to undergo chemotaxis.
- Protein nanopore sequencing utilizes membrane protein complexes such as "-Hemolysin, MspA ( Mycobacterium Smegmatis Porin A ) or CssG, which show great promise given their ability to distinguish between individual and groups of nucleotides.