phagosome उदाहरण वाक्य
उदाहरण वाक्य
- In a phagosome, superoxide can spontaneously form hydrogen peroxide that will undergo further reactions to generate reactive oxygen species ( ROS ).
- For this reason, as well as to avoid phagolysosomal fusion and death, " rickettsiae " must escape from the phagosome.
- Following internalization, the microbe is enclosed in a vesicular phagosome which then undergoes fusion with primary or secondary lysosomes, forming a phagolysosome.
- Upon stimulation, granulocytes and monocytes produce reactive oxygen metabolites ( superoxide anion, hydrogen peroxide, hypochlorous acid ) which destroy bacteria inside the phagosome.
- To escape from the phagosome, the bacteria secrete phospholipase D and hemolysin C . This causes disruption of the phagosomal membrane and allows the bacteria to escape.
- For example, when a macrophage ingests a pathogenic microorganism, the pathogen becomes trapped in a phagosome which then fuses with a lysosome to form a phagolysosome.
- They can internalize and kill many microbes, each phagocytic event resulting in the formation of a phagosome into which reactive oxygen species and hydrolytic enzymes are secreted.
- When the membranes of the phagosome and lysosome'collide', the lysosomal contents are discharged in an explosive manner and toxic molecules are released into the phagosome.
- When the membranes of the phagosome and lysosome'collide', the lysosomal contents are discharged in an explosive manner and toxic molecules are released into the phagosome.
- Phosphatidylinositol and Vps34-Beclin1 signalling pathways have been implicated to traffic the endocytosed phagosome to intracellular lysosomes, where fusion of the phagosome and the lysosome produces a phagolysosome.