pyridoxal phosphate उदाहरण वाक्य
उदाहरण वाक्य
- Each side of the dimer protein includes pyridoxal phosphate ( PLP ) bonded to the "'Lys280 "'residue of the tyrosine aminotransferase molecule.
- Pyridoxal phosphate ( a derivative of pyridoxine ) is required for d-aminolevulinic acid synthase, the enzyme responsible for the rate-limiting step in heme synthesis.
- Its toxicity stems primarily from the fact that it readily forms oximes with keto acids and aldehydes, especially the pyridoxal phosphate cofactor of many vitamin B 6-dependent enzymes.
- Glycogen phosphorylase has a pyridoxal phosphate ( PLP, derived from S N 1 fashion, resulting in the formation of a glucose molecule with a secondary carbocation at the 1 position.
- In each of the 19 pathways for the generation of chiral amino acids, the stereochemistry at the ?-carbon atom is established by a transamination reaction that involves pyridoxal phosphate.
- The mutations T67I and Q240E weaken the enzyme's affinity for pyridoxal phosphate, the co-factor vital to enzymatic function . Propargylglycine ( acidic beta hydrogen explicitly shown ).
- ALT ( and all aminotransferases ) require the coenzyme pyridoxal phosphate, which is converted into pyridoxamine in the first phase of the reaction, when an amino acid is converted into a keto acid.
- L-Phenylalanine is converted into L-tyrosine by the enzyme phenylalanine hydroxylase, with aromatic L-amino acid decarboxylase ( also known as DOPA decarboxylase ), with pyridoxal phosphate as the cofactor.
- "' Pyridoxal phosphate "'( PLP, pyridoxal 5'- phosphate, P5P ), the active form of vitamin B 6, is a coenzyme in a variety of enzymatic reactions.
- Structures of the three main molecules involved in chemical reaction catalyzed by the tyrosine aminotransferase enzyme are shown below : the amino acid tyrosine, the prosthetic group pyridoxal phosphate, and the resulting product 4-hydroxyphenylpyruvate.