remyelination उदाहरण वाक्य

उदाहरण वाक्य

1. GRNOPC1 is an embryonic stem cell based drug that is designed to treat specific forms of spinal cord injury through remyelination of damaged axons.
2. In addition, the interaction between transplanted cells and immune cells and the effect of inflammatory immune cells on remyelination have yet to be fully characterized.
3. Possible genes involved inside this pathway are TCF4 and OLIG2 which are both expressed in high amounts in areas where remyelination has failed from demyelinating diseases.
4. Studies that focused on oligodendrocytes made it possible to look at different molecular targets that could allow cells to be protected from demyelination and allow remyelination.
5. Julia Ruckh and fellow researchers have used parabiosis to study remyelination from adult stem cells to see if conjoining young with older mice could reverse or delay this process.
6. If polydendrocytes were capable of giving rise to myelinating oligodendrocytes, one would expect complete remyelination of pathologically demyelinated lesions such as those seen in multiple sclerosis ( MS ).
7. Combining immunomodulatory therapy with strategies to protect oligodendrocytes from further degeneration and enhance remyelination present a very real means to improve clinical outcomes for chronic progressive patients in the near future.
8. Possible explanations for remyelination failure include depletion of polydendrocytes over time, failure to recruit polydendrocytes to the demyelinated lesion, and failure of recruited polydendrocytes to differentiate into mature oligodendrocytes.
9. These markers are specific for the different processes that drive the formation of plaques : inflammation, myelin breakdown, astrogliosis, oligodendrocyte injury, neurodegeneration and axonal loss, and remyelination.
10. Anti-lingo-1 ( BIIB033 ) is a monoclonal antibody specific to the lingo-1 protein and is designed to promote remyelination ( the formation of new myelin on axons ) and neuroprotection.