complement cascade उदाहरण वाक्य

उदाहरण वाक्य

1. Mutations in three of the proteins in the complement cascade have been identified in patients with atypical HUS . Several chemotherapeutic drugs have also been shown to cause damage to the epithelial layer by reducing the ability for the cells to produce prostacyclin, ultimately resulting in chemotherapy-associated HUS, or C-HUS.
2. Sachs envisions " the ideal transgenic pig " as an animal with a variety of human genes working together against rejection : Genes to prevent human antibodies from binding to the pig organ, genes to inhibit the complement cascade and block endothelial-cell activation, genes that cause receptors to vital human growth factors and hormones to sprout on the pig cells.
3. The graft is given a break from humoral rejection when the complement cascade is interrupted, circulating antibodies are removed, or their function is changed, or there is a change in the expression of surface antigens on the graft . This allows the xenograft to up-regulate and express protective genes, which aid in resistance to injury, such as heme oxygenase-1 ( an enzyme that catalyzes the degradation of heme ).
4. In brief, the crucial role of C1q in the pathway is its importance as the first protein to start the complement cascade ( which ends in the destruction of the invading bacteria or virus ), and its ability to link the two important arms of the immune system  the innate immune system : a broad defence system; and the adaptive immune system : the strong immune response capable of remembering previous infections, allowing fast response against recurrent infections, meaning that people with a normal immune system don't continually catch the same cold or same strain of flu repeatedly.