frameshift mutation उदाहरण वाक्य
उदाहरण वाक्य
- Within the talk section there is some discussion about how impactful frameshift mutations are concerning the structure of proteins resulting from gene expression.
- An experiment to determine the accuracy of this newer sequencing method tested for 21 genes and had no false positive calls for frameshift mutations.
- The methods include providing a tissue or fluid sample and conducting gene analysis for frameshift mutation or a protein from this type of mutation.
- A frameshift mutation is not the same as a single-nucleotide polymorphism in which a nucleotide is replaced, rather than inserted or deleted.
- Such frameshift mutations can lead to deleterious effects on the peptide chain, including insertion of different amino acids or premature truncation of the protein.
- Mutations that disrupt the reading frame sequence by indels ( deletions ) of a non-multiple of 3 nucleotide bases are known as frameshift mutations.
- Frameshift mutations have been proposed as a source of biological novelty, as with the alleged creation of nylonase, however, this interpretation is controversial.
- An environmental study, specifically the production of UV-induced frameshift mutations by DNA polymerases deficient in 32 ?! 52 exonuclease activity was done.
- The mutants produced by Crick and Brenner could not produce functional rIIB protein because the insertion or deletion of a single nucleotide caused a frameshift mutation.
- However, many other genes have been discovered which did evolve by gene duplication followed by a frameshift mutation affecting at least part of the gene.