megakaryocyte उदाहरण वाक्य
उदाहरण वाक्य
- First, P-selectin is synthesized by megakaryocytes and endothelial cells, where it is sorted into the membranes of secretory granules.
- The first KLF, KLF1, originally known as Erythroid KLF ( EKLF ) is expressed only in red blood cells and megakaryocytes.
- miR-150 functions in hematopoiesis; it regulates genes whose downstream products encourage differentiating stem cells towards becoming megakaryocytes rather than erythrocytes.
- "' MegaCult "'is a collagen-based medium for the growth, detection and quantification of megakaryocyte progenitors.
- They are the functional equivalents of platelets, but circulate as intact mononuclear cells, and are not simply cytoplasmic fragments of bone marrow megakaryocytes.
- When megakaryocytes and endothelial cells are activated by agonists such as thrombin, P-selectin is rapidly translocated to the plasma membrane from granules.
- Thrombopoietin is bound to the surface of platelets by the mpl receptor ( CD 110 ) and destroyed, thereby reducing megakaryocyte exposure to the hormone.
- In preclinical human trials mature megakaryocytes which develop during " in vivo " treatment with Neumega were ultrastructurally, morphologically, and functionally normal.
- Thrombopoietin regulates the differentiation of megakaryocytes and platelets, but studies on the removal of the thrombopoietin receptor show that its effects on hematopoiesis are more versatile.
- Low platelets lead a higher degree of thrombopoietin exposure to the undifferentiated bone marrow cells, leading to differentiation into megakaryocytes and further maturation of these cells.