phosphonate उदाहरण वाक्य
उदाहरण वाक्य
- Most often, H-phosphonate building blocks are protected at the 5'- hydroxy group and at the amino group of nucleic bases A, C, and G in the same manner as phosphoramidite building blocks ( see below ).
- For example, the triazole-containing carbocycles by Von Itzstein and Pinto group and the phosphonate analogue of oseltamivir has been reported to show stronger activity resulted from a pertinent binding mode of phosphonate with three Arginine residues in the active site.
- For example, the triazole-containing carbocycles by Von Itzstein and Pinto group and the phosphonate analogue of oseltamivir has been reported to show stronger activity resulted from a pertinent binding mode of phosphonate with three Arginine residues in the active site.
- Deforolimus ( Ridaforolimus ) has C43 secondary alcohol moiety of the cyclohexyl group of Rapamycin that was substituted with phosphonate and phosphinate groups, preventing the high-affinity binding to mTOR and FKBP . Computational modelling studies helped the synthesise of the compound.
- The two ( phosphonate ) groups covalently linked to carbon determine both the name " bis " phospho " nate " and the function of the drugs . " Bis " refers to the fact that there are two such groups in the molecule.
- By installing phospho-serine, phospho-threonine or analogous phosphonate mimics into native proteins, researchers are able to perform in vivo studies to investigate the effects of phosphorylation by extending the amount of time a phosphorylation event occurs while minimizing the often-unfavorable effects of mutations.
- "' Leopold Horner "'( August 24, 1911 & ndash; October 5, 2005 ) was a German chemist who published a modified Wittig reaction using phosphonate-stabilized carbanions now called the Horner Wadsworth Emmons reaction ( HWE reaction ) or Horner-Wittig reaction.
- Alves FC, Donato P, Sherry AD, Zaheer A, Zhang S, Lubag AJ, Merritt ME, Lenkinski RE, Frangioni JV, Neves M, Prata MI, Santos AC, de Lima JJ, Geraldes CF . Silencing of phosphonate-gadolinium magnetic resonance imaging contrast by hydroxyapatite binding.
- The standard conditions for the Weinreb Nahm ketone synthesis are known to tolerate a wide variety of functional groups elsewhere in the molecule, including alpha-halogen substitution, N-protected amino acids, ?-? unsaturation, silyl ethers, various lactams and lactones, sulfonates, sulfinates, and phosphonate esters.
- In addition, the application of systemic ( potassium phosphonate ) with one and double injection ( 20 ml and 40 ml of fungicide for each injection frequency ), and semi-systemic ( metalaxyl ) fungicide showed better control compared to contact fungicides ( copper based fungicide ) in both locations that were used in the experiment.