replication fork उदाहरण वाक्य
उदाहरण वाक्य
- The clustering do "'rescue of stalled replication forks "'and favors normal progress of replication forks.
- Replicative polymerases form an asymmetric dimer at the replication fork by binding to sub-units of the clamp loading factor.
- At a replication fork arrested at an ICL, FAN1 nuclease action can catalyze incisions in the double-stranded region.
- When the replication fork reaches a site of DNA damage it stalls, which can lead to lethal double strand breaks.
- Unwinding of DNA at the origin and synthesis of new strands results in replication forks growing bi-directionally from the origin.
- In order for DNA replication to occur, a replication fork is created by enzymes called helicases which unwind the DNA helix.
- As with prokaryotes, two replisomes are required, one at each replication fork located at the terminus of the replication bubble.
- As replication forks spread bidirectionally from origins of replication at ( approximately ) equal speeds, then origin position can be inferred.
- The leading strand is the template strand that is being replicated in the same direction as the movement of the replication fork.
- FAN1 recruitment and its consequent activity restrain DNA replication fork progression and prevent chromosome abnormalities from occurring when DNA replication forks stall.