volume of distribution उदाहरण वाक्य
उदाहरण वाक्य
- Because of this low volume of distribution, it can be concluded that the medicine is thought to be confined in the plasma or liquid parts of the blood.
- The volume of distribution ( V d ) of lacosamide in plasma is 0.6 L / kg, which is close to the total volume of water.
- They are highly protein-bound in plasma ( typically > 95 % ), usually to albumin, so that their volume of distribution typically approximates to plasma volume.
- After being taken by mouth it is rapidly absorbed by the GI tract ( although absorption through the stomach is negligible ); its volume of distribution is roughly 50 L.
- However, if we do not make the initial volume of distribution vanishingly small, then we assume an instant mixing drug delivery in whatever volume the drug is delivered into.
- In dog testing, this compound with a carboxamide group called 13F, showed a great pharmacokinetical profile, a low clearance and adequate half-life and volume of distribution.
- Forced diuresis, hemodialysis, exchange transfusion, or hemoperfusion are unlikely to be of benefit in hastening the removal of venlafaxine, due to the drug's high volume of distribution.
- A metabolite of chloroquine hydroxycloroquine has a long half-life ( 32 56 days ) in blood and a large volume of distribution ( 580 815 L / kg ).
- It has a plasma half-life of 22min, mean clearance rate of 274 mL / kg / min, and apparent volume of distribution of 880 ?150 mL / kg.
- Clearance of a substance is sometimes expressed as the inverse of the time constant that describes its removal rate from the body divided by its volume of distribution ( or total body water ).