elongation factor उदाहरण वाक्य

उदाहरण वाक्य

1. Nosiheptide and other thiopeptide's mechanism of action stems from the tight binding on the 50S ribosomal subunit and inhibiting the activities of elongation factors, preventing protein synthesis.
2. During translation elongation, tRNA first binds to the ribosome as part of a complex with elongation factor Tu ( EF-Tu ) or its eukaryotic ( eEF-1 ) or archaeal counterpart.
3. It inhibits protein synthesis in the host cell through phosphorylation of the exotoxin A of Pseudomonas aeruginosa is another example of an AB toxin that targets the eukaryotic elongation factor 2.
4. This protein has also been shown to be a member of the NELF ( negative elongation factor ) protein complex that participates in the regulation of RNA polymerase II transcription elongation.
5. It is postulated that high expression and secretion of elongation factors from tumor tissues, combined with altered levels of eEF1A-derived bacterial peptides in neoplastic disease, may lead to autoimmunity in breast cancer.
6. It has been shown that 7SK RNA, a metazoan ncRNA, acts as a negative regulator of the RNA polymerase II elongation factor P-TEFb, and that this activity is influenced by stress response pathways.
7. The incorporation of selenocysteine into a protein requires the concerted action of an mRNA element called a sec insertion sequence ( SECIS ), a selenocysteine-specific translation elongation factor and a SECIS binding protein.
8. Decreases in the expression of genes involved in protein synthesis, such as elongation factor-2 and several ribosomal proteins, have been shown in the muscle of the mudsucker and gills of adult zebrafish after hypoxia exposure.
9. It was first identified during a search for RNA polymerase II-associated elongation factors in yeast; it directly interacts with RNA polymerase II ( RNAPII ) and is phosphorylated at casein kinase II ( CKII ) sites.
10. Once the nascent protein is released in termination, Ribosome Recycling Factor and Elongation Factor G ( EF-G ) function to release mRNA and tRNAs from ribosomes and dissociate the 70S ribosome into the 30S and 50S subunits.