epistasis उदाहरण वाक्य
उदाहरण वाक्य
- Empirically, beneficial mutations tend to have a smaller fitness benefit when added to a genetic background that already has high fitness : this is known as diminishing returns epistasis.
- Conversely, if mutations interact with one another by epistasis, the fitness landscape becomes rugged as the effect of a mutation depends on the genetic background of other mutations.
- The first understanding of biological processes requiring the Rab23 gene came from 2 independent mouse mutations in the gene and an epistasis analysis with mutations in the mouse shh gene.
- However, the effect of deleterious mutations tends on average to be very close to multiplicative, or can even show the opposite pattern, known as " antagonistic epistasis ".
- Conversely, when two mutations together lead to a less fit phenotype than expected from their effects when alone, it is called "'negative epistasis " '.
- The value of " K " controls the degree of epistasis in the NK model, or how much other loci affect the fitness contribution of a given locus.
- The ability of the E locus to override the coat colour directed by the B locus is a classical example of epistasis, where multiple genetic loci affect the same observed trait.
- It is believed that middle and long wave sensitive pigments appeared after the final stages of short wavelength sensitive opsin pigments evolved, and that trichromatic vision was formed through interprotein epistasis.
- In one of his last papers ( together with C . C . Cockerham, Genetics 1992 ) he clarified the influence of multiplicative gene action versus other types of epistasis in heterosis.
- Indicating that epistasis plays a major role in protein evolution an observation that in combination with the observations of several examples of parallel evolution, support the neutral network model mentioned above.