cellular death वाक्य

When pertaining to apoptosis, prolonged activation of P2X7 receptors can stimulate stress responses resulting in activated kinases responsible for inducing morphological and chemical changes, leading to apoptotic events and subsequent cellular death.
Missing from this cellular death are any signs of apoptotic induction such as characteristic changes to ATP . However, the involvement of RIPK1 has not been observed, suggesting that this necrosis is accidental in nature and not programmed.
In microangiopathy, the walls of the smaller blood vessels become so thick and weak that they cells and biological tissues ( called ischemia ) and leads to cellular death ( necrosis and gangrene, which in turn may require amputation ).
Cellular death due to necrosis does not follow the apoptotic signal transduction pathway, but rather various receptors are activated, and result in the loss of cell membrane integrity and an uncontrolled release of products of cell death into the extracellular space.