collagenase वाक्य

Activated MMP7 and APMA can increase the activity of collagenase-1, and MMP7 can also convert the latent progelatinase A to its active form.
In adrenocortical cells the trophic hormone ACTH induces expression of TIMP-1 and the increase in TIMP expression is also associated with decreased collagenase activity.
A genetically engineered version of a hormone secreted in pregnancy that allows a woman's skin to stretch, Relaxin works by boosting collagenase and decreasing collagen.
A study where patients were treated with these collagenase injections showed a recurrence rate of 67 % in the MCP joint and 100 % in the PIP joint.
As skin cells age, for example, their genes churn out more and more collagenase, an enzyme that breaks down proteins needed to keep wrinkles at bay.

Collagen, a key component of the animal extracellular matrix, is made through cleavage of pro-collagen by collagenase once it has been secreted from the cell.
Collagenase injection is a nonsurgical option to treat Dupuytren s disease and it provides the benefits of avoiding the potential surgical complications such as nerve injury, hematoma and skin necrosis.
In February 2010 the US Food and Drug Administration ( FDA ) approved injectable collagenase extracted from " Clostridium histolyticum " for the treatment of Dupuytren's contracture.
The main categories listed by the International Dupuytren Society in order of stage of disease are Radiation Therapy, Needle Aponeurotomy ( NA ), Collagenase Injection ( Xiaflex ) and Hand Surgery.
Other bonds hydrolysed include Gly35-Ile in the propeptide of collagenase 3, and Asn 341-Phe, Asp 441-Leu and Gln 354-Thr in the aggrecan interglobular domain