desmin वाक्य
"desmin" हिंदी में desmin in a sentenceउदाहरण वाक्य
- Aurora B targets a number of proteins that localize to the cleavage furrow, including the type-III intermediate filament proteins vimentin, desmin, and glial fibrillary acidic protein ( GFAP ).
- Keratin filaments in epithelial cells link to desmosomes ( desmosomes connect the cytoskeleton together ) through plakoglobin, desmoplakin, desmogleins, and desmocollins; desmin filaments are connected in a similar way in heart muscle cells.
- There is some evidence that desmin may also connect the sarcomere to the extracellular matrix ( ECM ) through desmosomes which could be important in signalling between the ECM and the sarcomere which could regulate muscle contraction and movement.
- The smooth muscle like cells of AMLs are morphologically and immunohistochemically similar to LAM cells, including reactivity with antibodies directed against actin, desmin, vimentin, and HMB-45 as well as estrogen and progesterone receptors.
- These binding partners suggest that syncoilin acts as a mechanical " linker " between the sarcomere Z-disk ( where desmin is localized ) and the dystrophin-associated protein complex ( where ?-dystrobrevin is localized ).
- Sequence analysis showed that human desmuslin was 32 % identical and 11 % similar to the amino acid sequence of chicken synemin, while the IF proteins vimentin and desmin are more than 80 % identical across the same species.
- FRCs also produce components of extracellular matrix, such as ER-TR7, fibrilin, laminin, fibronectin and intracellular components such as desmin and ?-actin smooth muscle that may influence the formation of the reticular fiber network.
- In adult desmin-null mice, hearts from 10 wk-old animals showed drastic alterations in muscle architecture, including a misalignment of myofibrils and disorganization and swelling of mitochondria; findings that were more severe in cardiac relative to skeletal muscle.
- It localizes at the Z-disk and has been shown to bind to ?-dystrobrevin, ?-actinin, and desmin to act as a mechanical linker in transmitting force laterally throughout the tissue, especially between the contractile myofibrils and extracellular matrix.
- An example of a WACA-proteins, which are mostly found in prokaryotes, is MinD . Examples for intermediate filaments, which have almost exclusively been found in animals ( i . e . eukaryotes ) are the lamins, keratins, vimentin, neurofilaments, desmin.