topoisomerase वाक्य

उदाहरण वाक्य

1. Amsacrine also expresses topoisomerase inhibitor activity, specifically inhibiting topoisomerase II ( compares with the better known agent etoposide ).
2. Use of topoisomerase inhibitors for antineoplastic treatments may lead to secondary neoplasms because of DNA damaging properties of the compounds.
3. This regulatory role may be directly associated with the role of topoisomerase II in disjoining sister chromatids prior to anaphase.
4. Inhibition of Aurora B due to loss of topoisomerase II seems to depend on BubR1 activity ( see below ).
5. This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription.
6. Structure of yeast topoisomerase II bound to a doubly nicked 34-mer duplex DNA ( PDB ID = 2RGR ).
7. In topoisomerase II-depleted cells, Aurora B and INCENP do not transfer to the central spindle in late mitosis.
8. Amrubicin acts by inhibiting topoisomerase II, and has been compared in clinical trials with topotecan, a Topoisomerase I inhibitor.
9. Amrubicin acts by inhibiting topoisomerase II, and has been compared in clinical trials with topotecan, a Topoisomerase I inhibitor.
10. It is a potent inhibitor of ribonuclease and topoisomerase II by preventing the binding of the nucleic acid to the enzyme.