decamethonium उदाहरण वाक्य
उदाहरण वाक्य
- In the process of binding, decamethonium actually activates ( depolarizes ) the motor endplate-but since the decamethonium itself is not degraded, the membrane remains depolarized and unresponsive to normal acetylcholine release.
- One of the outstanding recent contributions to pharmacology and therapeutics is his discovery, with Zaimis, of the actions of the methonium compounds-decamethonium a potent neuromuscular, and hexamethonium a potent ganglion blocking substance.
- In the 1950s and 1960s, the present-day concept of a neuromuscular blocking agent with a rapid onset and an ultra-short duration of action had not taken root : researchers and clinicians were still on the quest for potent but non-depolarizing replacements devoid of the histamine release and the dreaded " recurarizing " effects seen with tubocurarine and, more importantly, the absence of a depolarizing mechanism of action as seen with succinylcholine and decamethonium.
- From the 1950s through to the 1970s, the present-day concept of a neuromuscular blocking agent with a rapid onset and an ultra-short duration of action had not taken root : researchers and clinicians were still on the quest for potent but non-depolarizing replacements devoid of the histamine release and the dreaded " recurarizing " effects seen with tubocurarine and, more importantly, the absence of a depolarizing mechanism of action as seen with succinylcholine and decamethonium.