double strand break उदाहरण वाक्य

उदाहरण वाक्य

1. XRCC1 has an essential role in microhomology-mediated end joining ( MMEJ ) repair of double strand breaks.
2. When the replication fork reaches a site of DNA damage it stalls, which can lead to lethal double strand breaks.
3. Nibrin is a protein associated with the repair of double strand breaks ( DSBs ) which pose serious damage to a genome.
4. Subsequently, the double strand break is shown as being repaired through either homology-directed repair or non-homologous end joining.
5. Drugs that inhibit PARP1 cause multiple double strand breaks to form in this way, and in tumours with BRCA1, BRCA2 or PALB2
6. These carcinogens cause DNA damage such as DNA cross links and double strand breaks that often require repairs by pathways containing BRCA1 and BRCA2.
7. During repair of DNA double strand breaks, or repair of other DNA damage, incompletely cleared repair sites can cause epigenetic gene silencing.
8. Upon exposure to extreme dryness, " Bacillus subtilis " spores acquire DNA-double strand breaks and DNA-protein crosslinks.
9. These mutations involve double strand break repair impairment, which can result in arrest of spermatogenesis at stage IV of the seminiferous epithelium cycle.
10. Topoisomerase inhibitors are widely used as chemotherapeutics and cause replicating cells to undergo apoptosis by inducing double strand breaks that stall the replication fork.