nucleosome उदाहरण वाक्य
उदाहरण वाक्य
- Chromosomes are packaged by wrapping 147 nucleotides around an octamer of histone proteins, forming a nucleosome.
- There are also proteins involved in reassembling histones behind the replication fork to reestablish the nucleosome conformation.
- NBP-45 binds specifically to nucleosome core particles, and can function as a transcriptional activator.
- Nucleosome core particles are observed when chromatin in interphase is treated to cause the chromatin to unfold partially.
- Nucleosome remodeling has been found to cause, for instance, epigenetic silencing of DNA repair gene MLH1.
- Specific remodeling proteins are constantly altering the chromatin structure by breaking the bonds between the DNA and nucleosome.
- Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes.
- Histone H1 locks the nucleosome complex together, and it is the last protein to bind in the complex.
- Chromatin subunit models as well as the notion of the nucleosome were established in 1973 and 1974, respectively.
- A year later, she published a paper describing the opposing effects of H1 and HMGB1 on the nucleosome.