chlordiazepoxide उदाहरण वाक्य
उदाहरण वाक्य
- In tests of various benzodiazepine compounds, chlordiazepoxide was found to cause the most profound reduction in the turnover of 5HT ( serotonin ) in rats.
- In 1963, approval for use was given to diazepam ( Valium ), a " simplified " version of chlordiazepoxide, primarily to counteract anxiety symptoms.
- Chronic use of benzodiazepines, such as chlordiazepoxide, leads to the development of tolerance, with a decrease in number of benzodiazepine binding sites in mouse forebrain.
- Thus our article on the drug chlordiazepoxide ( commonly known as Librium ) is better than our benzodiazepine article, which covers the class of drugs to which Librium belongs.
- The first benzodiazepine, chlordiazepoxide ( " Librium " ), was synthesized in 1955 by Leo Sternbach while working at Hoffmann La Roche on the development of tranquilizers.
- An example in case is Roche, Switzerland for custom manufacturing precursors of the benzodiazepine class of tranquilizers, such as Librium ( chlordiazepoxide HCl ) and Valium ( diazepam ).
- The elimination half-life of diazepam and chlordiazepoxide, as well as other long half-life benzodiazepines, is twice as long in the elderly compared to younger individuals.
- Chlordiazepoxide ( Librium ), a long-acting benzodiazepine, is gaining attention as an alternative to diazepam in substance abusers dependent on benzodiazepines due to its decreased abuse potential.
- More than 1.2 million were taking diazepam or chlordiazepoxide, which are long-acting sedatives and sleeping pills that can make people groggy, forgetful and prone to falls.
- The safety profile of clonazepam during pregnancy is less clear than that of other benzodiazepines, and if benzodiazepines are indicated during pregnancy, chlordiazepoxide and diazepam may be a safer choice.