degranulation उदाहरण वाक्य
उदाहरण वाक्य
- C3a is an effector of the complement system with a range of functions including T cell activation and survival, angiogenesis stimulation, chemotaxis, mast cell degranulation, and macrophage activation.
- Blockade of TIGIT and PD-1 led to increased cell proliferation, cytokine production, and degranulation of TA-specific CD8 + T cells and TIL CD8 + T cells.
- Mast cell activation syndrome ( MCAS ) is an idiopathic immune disorder that involves recurrent and excessive mast cell degranulation and which produces symptoms that are similar to other mast cell activation disorders.
- These granules store a mixture of cytotoxic molecules, including many enzymes and antimicrobial peptides, that are released by a process called degranulation following activation of the granulocyte by an immune stimulus.
- Upon mast cell activation and degranulation, CPA3, the chymases, and tryptases are released in complexes with heparin proteoglycan . The parasitic nematode Ascaris produces CPA3 inhibitors, which increase its survival during infection.
- Activated mast cells and basophils undergo a process called degranulation, during which they release histamine and other inflammatory chemical mediators ( cytokines, interleukins, leukotrienes, and prostaglandins ) from their smooth-muscle contraction.
- Some studies have shown that edema attacks are associated with degranulation ( release of enzymes and mediators from eosinophils ), and others have demonstrated antibodies against endothelium ( cells lining blood vessels ) in the condition.
- Pulmonary emphysema can be induced in rats through acute exposure to sidestream tobacco smoke ( 30 cigarettes per day ) over a period of 45 days . Degranulation of mast cells contributing to lung damage has also been observed.
- In vertebrates, alpha-latrotoxin produces its effect through destabilisation of cell membranes and degranulation of GABA . Excess neurotransmitter activity leads to the clinical manifestations of envenomation, although the precise mechanisms are not well-understood.
- Possible class effects of antibodies include : Opsonisation, agglutination, haemolysis, complement activation, mast cell degranulation, and neutralisation ( though this class effect may be mediated by the Fab region rather than the Fc region ).