inotropic उदाहरण वाक्य

Cassaine can be defined as a specific inhibitor of monovalent cation transport and of Na +-K + ATPase; the result being an inotropic effect on cardiac muscle.
Because of the negative inotropic effects of flecainide, it should be used with caution in individuals with depressed ejection fraction, and may worsen congestive heart failure in these individuals.
Noradrenaline ( a . k . a . norepinephrine ) is an inotrope and has a positive inotropic effect on heart muscle, when binding to beta-1 adrenergic receptors on this tissue.
Inotropes stimulate cardiac muscle ( i . e . digoxin is an inotropic agent ) whereas ionotropic agents generally requires a ligand to bind causing opening / closing of a ligand receptor gated channel.
Disopyramide s particular efficacy is due to its potent negative inotropic effects; in head-to-head comparison, it is more effective for gradient reduction than either beta-blocker or verapamil.

It was found to depress the tonicity of coronary vessels, improve myocardial metabolism ( so that heart can sustain hypoxia better ) and also exert a positive chronotropic and inotropic effects, thereby not precipitating angina pectoris.
Activation of ? 1 receptors induces positive inotropic, chronotropic output of the cardiac muscle, leading to increased heart rate and blood pressure, secretion of ghrelin from the stomach, and renin release from the kidneys.
For instance,-- ATPase found in the membrane of heart cells is an important target of cardiac glycosides ( for example digoxin and ouabain ), inotropic drugs used to improve heart performance by increasing its force of contraction.
It is indicated when parenteral therapy is necessary for inotropic support in the short-term treatment of patients with cardiac decompensation due to depressed contractility, which could be the result of either organic heart disease or cardiac surgical procedures.
"' Pharmacological modulation of contractility "'is performed with cardioactive "'inotropic agents "'( positive or negative inotropes ) being present in the blood stream and affecting the rate of contraction of myocardial fibers.