megaloblast मीनिंग इन हिंदी

He demonstrated the existence of nucleated red blood cells, which he subdivided into normoblasts, megaloblasts, microblasts and poikiloblasts; he had discovered the precursors of erythrocytes.
Nucleated red blood cells in mammals consist of two forms : normoblasts, which are normal erythropoietic precursors to mature red blood cells, and megaloblasts, which are abnormally large precursors that occur in megaloblastic anemias.
Classically, these megaloblastic types of anemias are associated also with more specific features, such as megaloblasts in the bone marrow, the presence of ovalocytes in the ( peripheral ) blood smear, and the pathognomonic presence of hypersegmented neutrophils.
The pathological state of megaloblastosis is characterized by many large immature and dysfunctional red blood cells ( megaloblasts ) in the bone marrow and also by hypersegmented neutrophils ( those exhibiting five or more nuclear lobes ( " segments " ), with up to four lobes being normal ).

संज्ञा.

abnormally large red blood cell present in pernicious anemia and folic acid deficiency