melanoblast मीनिंग इन हिंदी

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Conditions associated with abnormalities in the migration of melanoblasts are known collectively as piebaldism.
In melanogenesis, melanoblasts migrate from the neural crest to their appropriate locations in the epidermis.
Like for melanoblasts, this helps guide the cells to their appropriate locations in the body.
Melanocyte stem cells are called melanoblasts.
Melanoblasts express the KIT receptor, and it is believed that SCF guides these cells to their terminal locations.
The resulting pattern appears symmetrical only if melanoblasts migrate to both locations of a pair and proliferate to the same degree in both locations.
Location of the pigmented spots is dependent on the migration of melanoblasts ( primordial pigment cells ) from the neural crest to paired bilateral locations in the skin of the early embryo.
The functional cooperation between MITF and the lymphoid enhancing factor ( LEF-1 ) results in a synergistic transactivation of the dopachrome tautomerase gene promoter, which is an early melanoblast marker.

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