• विविध रंजकता |
metachromasia मीनिंग इन हिंदी
metachromasia उदाहरण वाक्य
उदाहरण वाक्य
अधिक: आगे- The underlying mechanism for metachromasia requires the presence of polyanions within the tissue.
- He also studied the metachromasia of nucleic acids.
- Hence, proximity of the dye molecules was the key parameter in defining metachromasia.
- Although metachromasia was observed and described since 1875, by Ranvier and others, it was the German scientist Paul Ehrlich ( 1854-1915 ) who gave its name and studied it more extensively.
- The modern understanding of metachromasia was advanced by Belgian histologist Lucien Lison, who studied it between 1933 and 1936 and ascertained its value in the quantitative determination of sulfate esters of high molecular weight.
- Cell and tissue structures that have high concentrations of ionized sulfate and phosphate groups such as the ground substance of cartilage, heparin-containing granules of mast cells, and rough endoplasmic reticulum of plasma cells exhibit metachromasia.
- More recently, Karlheinz Toepfer published in 1970 spectral shifts with increasing concentration of the thiazine dyes that matched the spectra of dye : heparin mixtures, showing clearly that metachromasia, corresponding to the colour of stained cartilage, could be reproduced by high concentration of the dye alone in solution.
- The greater the degree of stacking, the greater the metachromatic shift . Thus, hyaluronic acid, lacking sulphate groups and with only moderate charge density, causes slight metachromasia; chondroitin sulfate, with an additional sulfate residue per GAG saccharide dimer, is an effective metachromatic substrate, whilst heparin, with further N-sulfation, is strongly metachromatic.