somatomedin मीनिंग इन हिंदी

उदाहरण वाक्य

1. Several structures has been reported for the Somatomedin B domain.
2. The somatomedin B domain is a close-knit disulfide knot, with 4 disulfide bonds within 35 residues.
3. The somatomedin B domain of vitronectin binds to plasminogen activator inhibitor-1 ( PAI-1 ), and stabilizes it.
4. The Somatomedin B domain interacts with the urokinase receptor, and this interaction has been implicated in cell migration and signal transduction.
5. The symptoms include decreased growth hormone ( GH ) and somatomedin secretion, very short stature, weight that is inappropriate for the height, and immature skeletal age.
6. The cDNA encodes a protein of 1, 404 amino acids ( human A isoform ) with a somatomedin B homology domain, heparin-binding domains, multiple mucin-like repeats, a hemopexin domain, and an aggregation domain.
7. Cys-rich somatomedin B-like domains are found in a number of proteins, including plasma-cell membrane glycoprotein ( which has nucleotide pyrophosphate and alkaline phosphodiesterase I activities ) and placental protein 11 ( which appears to possess amidolytic activity ).
8. The SMB domain of vitronectin has been demonstrated to interact with both the urokinase receptor and the plasminogen activator inhibitor-1 ( PAI-1 ) and the conserved cysteines of the NPP1 somatomedin B-like domain have been shown to mediate homodimerization.
9. Associated abnormalities vary and may include facial dysmorphism, upslanting palpebral fissures, hypertelorism, cleft palate, genital anomalies, mild developmental delay, ureterocele, smooth muscle hamartoma, nevus lipomatosus, Laron syndrome ( dwarfism with high growth hormone and low somatomedin activity ), and other defects.